Dr. Nejat F. Eczacıbaşı completed his studies in 1942, returned home, and established the foundation of Turkey's first modern pharmaceutical production facility, Eczacıbaşı Pharmaceutical Industry in 1952. The company lead Turkish pharmaceutical industry with its high standards and innovations.

To benefit from the changes in Turkey, Eczacıbaşı Pharmaceutical Industry started to seek strategic partners within the global pharmaceutical market, in 2007, it transferred 75 per cent of their shares in Eczacıbaşı Sağlık Ürünleri and Eczacıbaşı Özgün Kimya to Zentiva N.V., one of Europe's leading companies in the field of equivalent pharmacy field. The transfer of the remaining 25 percent partnership took place in July 2009.

The title of Eczacıbaşı Pharmaceutical Industry has changed and the new title ''Eczacıbaşı Pharmaceutical and Industrial Investment Co'' was published in Turkish Trade Registry Gazette on 24 November 2008, No. 7195 edition. Eczacıbaşı İlaç, Sınai ve Finansal Yatırımlar, which does not have production activities, has a kind of holding structure with its existing subsidiaries, business partnerships and affiliates. Within this structure, it directly engages in real estate development activities and acts as a strategic partner in healthcare, building products and other industries.